Obesity

cancer and obesity

Obese people often have chronic low-level inflammation which can cause DNA damage that leads to cancer.  Obese patients are more likely than normal-weight individuals to have disorders that cause chronic local inflammation and that are risk factors for the developing of certain type of cancers. Such as Barrett oesophagus, gallbladder cancer .adipose tissue produces excess amounts of estrogen, elevated levels of estrogen leads to increased risks of breast, endometrial, ovarian, and some other cancers. Obese people often have increased insulin levels in blood and insulin-like growth factor-1 (IGF-1). High levels of insulin and IGF-1 promotes the development of colon, kidney, prostate, and endometrial cancers.