Biography
May Tsai is currently a doctor at St Vincent’s Hospital Melbourne after completing her MBBS/B Med Sci at the University of Melbourne in 2013. She has been involved in cardiovascular medicine research with Professor Andrew Wilson and has published in the International Journal of Cardiology. Her area of interests includes cardiology and perioperative medicine. She is currently completing Postgraduate Certificate/Diploma in Clinical Ultrasound.
Abstract
AIM/OBJECTIVES
The demand for bariatric procedures has risen dramatically in recent years due to the growing obesity epidemic. Whilst there are many published papers on bariatric surgery, there is limited information within the rural Australian context. Our objective was to assess results of weight loss and complications of laparoscopic sleeve gastrectomy (LSG) performed in rural Australia, describing patient characteristics and assessing significant predictors of outcomes.
METHODS:
Review of 141 consecutive patients who underwent LSG at a rural Australian hospital was obtained. Data on patient demographics, mean weight loss and complications were collected. Significant predictors for length of stay calculated using multivariate analyses.
RESULTS:
141 patients underwent LSG. Mean (SD) preoperative body mass index was 45kg/m2 (7.8kg/m2). Mean follow-up and length of hospital stay were 15months (10months) and 2.2 days (0.78days) respectively. Mean excess weight loss (SD, available patient data) was 30% (17%, 141 patients), 41% (20%, 56 patients), 51% (21%, 36 patients), 68% (13%, 11 patients) and 65% (16%, 4 patients) at 3, 6, 9, 18 and 24 months, respectively.
3(2.1%) patients required return to theatre for management of staple line leak. Post-op blood transfusion rate was 2.1%(3patients). There were no mortality. All-cause 30-day readmission rate was 7.1% (10 patients).
Adjusted for preoperative characteristics, significant predictors of hospital stay duration were female sex (p=0.008), past history of hypercholesterolemia (p=0.012) and operation time (p=0.049).
CONCLUSIONS:
Laparoscopic sleeve gastrectomy can be performed safely and effectively in rural Australia. Significant pre-operative predictors of length of hospital stay include female sex and past history of hypercholesterolemia.
Biography
Ines Gouaref is conducting her Phd Thesis on the link between trace elements, type 2 diabetes and hypertension in the University of Science and Technology Houari Boumediene, Algiers, Algeria. She started her Phd thesis in 2011 and participated to many national and international scientific events to present her conclusions on the diabetes in Algeria, north Africa.
Abstract
In the systemic hypertension (SHT), the relationship between antioxidants mineral trace elements (AMTE) is very complex during oxidative stress, being mediated by endothelial dysfunction, dyslipidemia and inflammation. We investigated the AMTE status, particularly Manganese, selenium, copper and Zinc on the SHT control, and their interaction with the cardio metabolic syndrome (CMS) clusters. Design and method: The study was undertaken on 278 Algerian hypertensive subjects who were divided in 2 groups according to systolic blood pressure (SBP) < 140 or > 140 mmHg value, and diastolic blood pressure (DBP) < 90 or > 90 mmHg value; attesting for a good or poor metabolic control of SHT, respectively. The CMS was defined according to NCEP-ATPIII. Insulin resistance was evaluated by HOMA-IR model. The blood AMTE, were evaluated by atomic mass spectrometry.
Results: The AMTE status showed that hypertensive patients with CMS are mainly depleted. The selenium was positively correlated with glutathion peroxidase activity. The copper and Zinc are increased, causing an increase in the ratio Cu/Zn associated to decrease the SOD activity.
Conclusion: Our results suggest that AMTE play a crucial role in antioxidant capacity in SHT and we hypothesize that antioxidant defense is impaired in mitochondria, which makes this cell organelle a true therapeutic target in SHT. The AMTE can be considered as an insidious biomarkers endothelial dysfunction.