Sunghyen Lee
National Institute of Agricultural Sciences (NIAS), South Korea
Title: Supplementary effects of black rice (Oryza sativa L.) aleurone layer extract on body fat, serum lipid, and serum hormone levels in ovariectomized rats
Biography
Biography: Sunghyen Lee
Abstract
This study was conducted to evaluate suppressive effects of black rice (Oryza sativa L.) aleurone layer extract (BRE) on body fat, serum lipid, and hormone levels in ovariectomized rats. The rats were divided into five groups (n=8/group): Sham operated group (S); ovariectomized control group (OVX); ovariectomized group treated with isoflavone 10 mg/kg for body weight (IF); ovariectomized group treated with BRE at 30 or 90 mg/kg for body weight (BRE-30 or -90). High fat diet (45% calories from fat) was fed to all rats for 12 weeks. Body weight gain, body fat weight, and adiposity index increased in the OVX group, but they significantly decreased in IF or BRE supplementation. Serum triacylglyceride and leptin levels decreased in BRE groups while serum adiponectin level significantly increased compared to that of the OVX group. Hepatic total lipid, triacylglyceride, or cholesterol levels increased in the OVX group, but they decreased in BRE supplementation (p>0.05). These data suggest that black rice aleurone layer may be a useful food source to decrease obesity and its related diseases by modulating lipid metabolism in estrogen-deficiency model.
